AD822, AW199, AW200 and AW201 antibodies against the human Fas receptor (CD95) bind the surface of HEK293 cells as revealed by flow cytometry

Authors

  • Soyan Dawit
  • Meg-Mai-Ly Diep
  • Odyssee Ferrillo
  • Maxime Guertler
  • Catalina Gureu
  • Margaux Herren
  • Simon leyss
  • Karolina Liborova
  • Marie Maître
  • Livia Manghetti
  • Lucie Mencier
  • Lana Moudarres
  • Gaelle Najand
  • Laura Roch
  • Audrey Ruetsche
  • Valerie Schwitzguebel
  • Wissem Seddiki
  • Paola Soulie
  • Nneka Anagbogu
  • Kenza Bennani
  • Elise Brun
  • Hannah Butterworth
  • Jennifer Carry
  • Jean-Pierre Aubry-Lachainaye
  • Cécile Gameiro
  • Stéphane Durual
  • Tania Jauslin
  • Cyril Guilhen

DOI:

https://doi.org/10.24450/journals/abrep.2023.e1143

Abstract

The recombinant antibodies AD822, AW199, AW200 and AW201 bind HEK293 cells expressing the human Fas receptor protein as assessed by flow cytometry.

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References

Chodorge M, Züger S, Stirnimann C, Briand C, Jermutus L, Grütter MG, et al. A series of Fas receptor agonist antibodies that demonstrate an inverse correlation between affinity and potency. Cell Death Differ. 2012 Jul;19(7): 1187‑95. PMID: 22261618.

Haruyama H, Ito S, Miyadai K, Takahashi T, Kawaida R, Takayama T, et al. Humanization of the Mouse Anti-Fas Antibody HFE7A and Crystal Structure of the Humanized HFE7A Fab Fragment. Biological and Pharmaceutical Bulletin. 2002;25(12): 1537‑45. PMID: 12499636.

Uhlén M, Fagerberg L, Hallström BM, et al. Proteomics. Tissue-based map of the human proteome. Science. 2015;347(6220):1260419. PMID: 25613900

Kamon S, Tomokazu M, Shigekazu N, Sung CM, Maximiliano V. Anti-Fas ligand antibody and assay method using the anti-Fas ligand antibody. United States, US6114507. 2000.

Nalivaiko K, Hofmann M, Kober K, Teichweyde N, Krammer PH, Rammensee HG, et al. A Recombinant Bispecific CD20×CD95 Antibody With Superior Activity Against Normal and Malignant B-cells. Mol Ther. 2016 Feb;24(2): 298‑305. PMID: 26581163.

Itoh N, Yonehara S, Ishii A, et al. The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis. Cell. 1991;66(2):233-243. PMID: 1713127.

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Published

2023-03-29 — Updated on 2023-04-25

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How to Cite

1.
Dawit S, Diep M-M-L, Ferrillo O, Guertler M, Gureu C, Herren M, leyss S, Liborova K, Maître M, Manghetti L, Mencier L, Moudarres L, Najand G, Roch L, Ruetsche A, Schwitzguebel V, Seddiki W, Soulie P, Anagbogu N, Bennani K, Brun E, Butterworth H, Carry J, Aubry-Lachainaye J-P, Gameiro C, Durual S, Jauslin T, Guilhen C. AD822, AW199, AW200 and AW201 antibodies against the human Fas receptor (CD95) bind the surface of HEK293 cells as revealed by flow cytometry. Antib. Rep. [Internet]. 2023 Apr. 25 [cited 2023 Jun. 1];6(1):e1143. Available from: https://oap.unige.ch/journals/abrep/article/view/1143

Issue

Vol. 6 No. 1 (2023)

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Article

License

Copyright (c) 2023 Soyan Dawit, Meg-Mai-Ly Diep, Odyssee fer, Maxime Guertler, Catalina Gureu, Margaux Herren, Simon leyss, Karolina Liborova, Marie Maître, Livia Manghetti, Lucie Mencier, Lana Moudarres, Gaelle Najand, Laura Roch, Audrey Ruetsche, Valerie Schwitzguebel, Wissem Seddiki, Paola Soulie, Nneka Anagbogu, Kenza Bennani, Elise Brun, Hannah Butterworth, Jennifer Carry, Jean-Pierre Aubry-Lachainaye, Cécile Gameiro, Stéphane Durual, Tania Jauslin, Cyril Guilhen

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This work is licensed under a Creative Commons Attribution 4.0 International License.

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