The AW519 antibody specifically detects αvβ6 integrin by flow cytometry

Authors

  • Jérémy Kessler
  • Michael Bachmann
  • Bernhard Wehrle-Haller

DOI:

https://doi.org/10.24450/journals/abrep.2022.e857

Abstract

The recombinant antibody AW519 detects specifically the β6 (ITGB6) subunit of αVβ6 integrin on MDA-MB-168 cells and on NIH-3T3 cells when transfected with human β6 integrin as demonstrated with flow cytometry.

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References

Bachmann M, Kukkurainen S, Hytönen VP, Wehrle- Haller B. Cell adhesion by integrins. Physiol Rev. 2019; 99:1655-99. PMID: 31313981.

Weinreb PH, Simon KJ, Rayhorn P, et al. Function- blocking integrin alphavbeta6 monoclonal antibodies: distinct ligand-mimetic and nonligand-mimetic classes. J Biol Chem. 2004; 279(17):17875-87. PMID: 14960589.

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Published

2022-06-29

How to Cite

1.
Kessler J, Bachmann M, Wehrle-Haller B. The AW519 antibody specifically detects αvβ6 integrin by flow cytometry. Antib. Rep. [Internet]. 2022 Jun. 29 [cited 2022 Aug. 14];5(2):e857. Available from: https://oap.unige.ch/journals/abrep/article/view/857

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