The Impact of SARS-CoV-2 on the Brain: It Is All in Your Head

Authors

DOI:

https://doi.org/10.25250/thescbr.brk677

Keywords:

Brain, COVID-19, SARS-CoV-2, Neuroinflammation, neurodegeneration

Abstract

What is going on with SARS-CoV-2 infection and your brain? Even in mild infection there may be neurological injury that affects recovery. In our study, brain tissue recovered from SARS-CoV-2 infected non-human primates revealed microbleeds, neuron injury and death, and evidence of brain hypoxia, all of which may cause long-lasting neurological symptoms after infection.

Author Biographies

Meredith G. Mayer, Tulane University

PhD student

Tracy Fischer, Tulane University

Professor

Original article reference

Rutkai, I., Mayer, M. G., Hellmers, L. M., Ning, B., Huang, Z., Monjure, C. J., Coyne, C., Silvestri, R., Golden, N., Hensley, K., Chandler, K., Lehmicke, G., Bix, G. J., Maness, N. J., Russell-Lodrigue, K., Hu, T. Y., Roy, C. J., Blair, R. v., Bohm, R., … Fischer, T. (2022). Neuropathology and virus in brain of SARS-CoV-2 infected non-human primates. Nature Communications, 13(1), 1745. https://doi.org/10.1038/s41467-022-29440-z

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Published

2023-02-15

Issue

Section

Neurobiology