Does bacteria control our appetite?

Authors

DOI:

https://doi.org/10.25250/thescbr.brk668

Keywords:

Appetite, Gut Microbiota, Gut-Brain Interaction, Bacteria, Peptides, Signalling

Abstract

The gut-brain pathway has been the center of many studies in the past few years, but the mechanisms driving this interaction are still poorly understood. In our work we reveal how parts of a bacterium’s cell wall are able to reach the brain and decrease the activity of certain neurons controlling appetite.

Author Biography

Ilana Gabanyi, Institut Pasteur

Postdoctoral Fellow

Original article reference

Gabanyi, I., Lepousez, G., Wheeler, R., Vieites-Prado, A., Nissant, A., Wagner, S., Moigneu, C., Dulauroy, S., Hicham, S., Polomack, B., Verny, F., Rosenstiel, P., Renier, N., Boneca, I. G., Eberl, G., & Lledo, P.-M. (2022). Bacterial sensing via neuronal Nod2 regulates appetite and body temperature. Science, 376(6590). https://doi.org/10.1126/science.abj3986

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Published

2023-01-18

Issue

Vol. 9 No. 1 (2023): TheScienceBreaker

Section

Neurobiology

License

Some rights reserved 2023 Ilana Gabanyi

Creative Commons License

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.