A laser proton accelerator targeting tumors in mice

Florian Kroll

doi:10.25250/thescbr.brk716

Authors

Florian Kroll Helmholtz-Zentrum Dresden-Rossendorf https://orcid.org/0000-0002-0275-9892

DOI:

https://doi.org/10.25250/thescbr.brk716

Keywords:

Laser, Tumor, Radiobiology, Plasma accelerator, FLASH

Abstract

High-power short-pulse lasers can generate intense but fluctuating bunches of energetic protons. We demonstrate a new level of stability for laser-driven proton sources that allowed us to successfully perform the world-wide first tumor irradiation study in mice with this novel radiation source.

Author Biography

Florian Kroll, Helmholtz-Zentrum Dresden-Rossendorf

PostDoctoral Researcher and Beamline scientist

Original article reference

Kroll, F., Brack, F.-E., Bernert, C., Bock, S., Bodenstein, E., Brüchner, K., Cowan, T. E., Gaus, L., Gebhardt, R., Helbig, U., Karsch, L., Kluge, T., Kraft, S., Krause, M., Lessmann, E., Masood, U., Meister, S., Metzkes-Ng, J., Nossula, A., … Beyreuther, E. (2022). Tumour irradiation in mice with a laser-accelerated proton beam. Nature Physics, 18(3), 316–322. https://doi.org/10.1038/s41567-022-01520-3