How platelets pull the strings
DOI:
https://doi.org/10.25250/thescbr.brk692Keywords:
Platelets, Wound healing, Mechanobiology, Super-Resolution MicroscopyAbstract
Without platelets, humans might have bled to death even with the tiniest of wounds. But is their only function to stop blood loss? New results suggest that they could also help in starting to heal a wound by forming new specialized tissue. These findings pave the way for improvements in implanted medical devices and treatment options for those suffering from frequent bleeding.
Original article reference
Lickert, S., Kenny, M., Selcuk, K., Mehl, J. L., Bender, M., Früh, S. M., Burkhardt, M. A., Studt, J.-D., Nieswandt, B., Schoen, I., & Vogel, V. (2022). Platelets drive fibronectin fibrillogenesis using integrin αIIbβ3. Science Advances, 8(10). https://doi.org/10.1126/sciadv.abj8331

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