How platelets pull the strings

Authors

DOI:

https://doi.org/10.25250/thescbr.brk692

Keywords:

Platelets, Wound healing, Mechanobiology, Super-Resolution Microscopy

Abstract

Without platelets, humans might have bled to death even with the tiniest of wounds. But is their only function to stop blood loss? New results suggest that they could also help in starting to heal a wound by forming new specialized tissue. These findings pave the way for improvements in implanted medical devices and treatment options for those suffering from frequent bleeding.

Author Biography

Sebastian Lickert, Laboratory of Applied Mechanobiology

Research group leader

Original article reference

Lickert, S., Kenny, M., Selcuk, K., Mehl, J. L., Bender, M., Früh, S. M., Burkhardt, M. A., Studt, J.-D., Nieswandt, B., Schoen, I., & Vogel, V. (2022). Platelets drive fibronectin fibrillogenesis using integrin αIIbβ3. Science Advances, 8(10). https://doi.org/10.1126/sciadv.abj8331

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Published

2023-03-28

Issue

Section

Health & Physiology