Can CBD help to combat COVID variants?

Marsha Rosner; Long Nguyen

doi:10.25250/thescbr.brk704

Authors

Marsha Rosner University of Chicago https://orcid.org/0000-0001-6586-8335
Long Nguyen University of Chicago

DOI:

https://doi.org/10.25250/thescbr.brk704

Keywords:

COVID-19, SARS-CoV-2, Cannabidiol (CBD), Cannabis

Abstract

There is an urgent need to find new treatments that complement the use of vaccines and antiviral drugs to combat the COVID-19 pandemic. Our interdisciplinary research team uncovered evidence that cannabidiol (CBD), a non-psychoactive compound produced by cannabis plants, has the potential to inhibit SARS-CoV-2, the virus that causes COVID.

Author Biographies

Marsha Rosner, University of Chicago

Professor

Long Nguyen, University of Chicago

Postdoctoral Research Fellow

Original article reference

Nguyen, L. C., Yang, D., Nicolaescu, V., Best, T. J., Gula, H., Saxena, D., Gabbard, J. D., Chen, S.-N., Ohtsuki, T., Friesen, J. B., Drayman, N., Mohamed, A., Dann, C., Silva, D., Robinson-Mailman, L., Valdespino, A., Stock, L., Suárez, E., Jones, K. A., … Rosner, M. R. (2022). Cannabidiol inhibits SARS-CoV-2 replication through induction of the host ER stress and innate immune responses. Science Advances, 8(8). https://doi.org/10.1126/sciadv.abi6110