Solving the puzzle behind COVID-19 induced smell loss
DOI:
https://doi.org/10.25250/thescbr.brk640Keywords:
COVID-19, anosmia, nuclear organization, olfactory receptorsAbstract
The SARS-CoV-2 virus rarely infects olfactory sensory neurons, yet causes widespread anosmia. Explaining this seeming paradox is that odor detection is impaired due to virus-mediated disruption of nuclear architecture that results in olfactory receptor and associated downregulation of signaling genes.
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Some rights reserved 2022 Marianna Zazhytska, Jonathan B. Overdevest
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