Preventing the perfect crime

Authors

DOI:

https://doi.org/10.25250/thescbr.brk804

Keywords:

protein, cell death

Abstract

Every cell is a crime scene. There is a constant struggle between the criminals plotting to kill the cell and the detectives trying to prevent the crime. Triggering cell death requires strengthening the criminals while keeping a cell alive requires more detectives. Manipulating this crime for either side opens treatment options for various diseases such as cancer.

Author Biographies

  • Christina Elsner, University of Geneva

    Postdoctoral Research Fellow

  • Anton Hanke, Department of Pharmaceutical Sciences

    PhD student

Original article reference

Elsner, C.; Hanke, A.; Vadas, O.; Gervasio, F. L.; Bordignon, E. Structural and Dynamic

Basis of Indirect Apoptosis Inhibition by Bcl-xL: A Case Study with Bid, 2025.

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Published

2026-03-09