Preventing the perfect crime

Authors

DOI:

https://doi.org/10.25250/thescbr.brk804

Keywords:

protein, cell death

Abstract

Every cell is a crime scene. There is a constant struggle between the criminals plotting to kill the cell and the detectives trying to prevent the crime. Triggering cell death requires strengthening the criminals while keeping a cell alive requires more detectives. Manipulating this crime for either side opens treatment options for various diseases such as cancer.

Author Biographies

Christina Elsner, Université de Genève

Postdoctoral Research Fellow

Anton Hanke, Department of Pharmaceutical Sciences

PhD student

Original article reference

Elsner, C.; Hanke, A.; Vadas, O.; Gervasio, F. L.; Bordignon, E. Structural and Dynamic

Basis of Indirect Apoptosis Inhibition by Bcl-xL: A Case Study with Bid, 2025.

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Published

2026-03-09