Awakening the thymus to cure SARS-CoV-2 infection: a matter of genes

Stefano Marullo; Cheynier Remi

doi:10.25250/thescbr.brk787

Authors

Stefano Marullo Inserm https://orcid.org/0000-0001-9604-9973
Cheynier Remi Inserm https://orcid.org/0000-0003-1146-660X

DOI:

https://doi.org/10.25250/thescbr.brk787

Keywords:

COVID-19, Thymus, genetic polymorphism, immune response

Abstract

Establishing an appropriate immune response is essential to recover from viral diseases such as COVID-19.The thymus, an organ of the immune system, plays a vital role in producing new T-lymphocytes that help eliminate the virus that causes COVID-19. We recently discovered that a genetic trait determines the effectiveness of thymic activity in fighting this virus, and thus the clinical outcome.

Author Biographies

Stefano Marullo, Inserm

Research Director

Cheynier Remi, Inserm

Research Director

Original article reference

Hélène M. Roux et al., Genetically determined thymic function affects strength and duration of immune response in COVID patients with pneumonia. Sci. Adv., 9 (38), eadh7969. DOI: 10.1126/sciadv.adh7969