Stressing the gut-brain axis

Authors

DOI:

https://doi.org/10.25250/thescbr.brk778

Keywords:

IBD, psychological stress, enteric nervous system

Abstract

It is widely known that psychological stress influences many aspects of our health. This is particularly true in the case of inflammatory bowel disease (IBD), a widespread disease of the gut. We found that psychological stress leads to inflammation of the gut by changing the gut-residing nervous system, which may inform therapeutic approaches in the future.

Author Biographies

Niklas Blank, University of Pennsylvania, Philadelphia, USA; University of Freiburg, Freiburg, Germany

PhD student

Markus Schneider, RWTH Aachen University

Assistant Professor

Christoph Thaiss, University of Pennsylvania

Assistant Professor

Original article reference

Schneider, K. M., Blank, N., Alvarez, Y., Thum, K., Lundgren, P., Litichevskiy, L., Sleeman, M., Bahnsen, K., Kim, J., Kardo, S., Patel, S., Dohnalová, L., Uhr, G. T., Descamps, H. C., Kircher, S., McSween, A. M., Ardabili, A. R., Nemec, K. M., Jimenez, M. T., … Thaiss, C. A. (2023). The enteric nervous system relays psychological stress to intestinal inflammation. Cell, 186(13), 2823-2838.e20. https://doi.org/10.1016/j.cell.2023.05.001

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Published

2024-01-31

Issue

Vol. 10 No. 1 (2024): TheScienceBreaker

Section

Health & Physiology

License

Some rights reserved 2023 Niklas Blank, Markus Schneider, Christoph Thaiss

Creative Commons License

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.