Mathematical modeling and tumor avatars: What’s the link?

Authors

DOI:

https://doi.org/10.25250/thescbr.brk730

Keywords:

colorectal cancer, personalized treatment, organoids, drug combinations

Abstract

We introduce a new approach for designing personalized treatment for colorectal cancer patients, by combining patient-derived samples and mathematical modeling. This unique strategy is tailored specifically to individual patients, as we go from bench to bedside and back.

Author Biographies

  • George Ramzy, University of Geneva

    Postdoctoral Research Fellow

  • Patrycja Nowak-Sliwinska, University of Geneva

    Associate Professor

Original article reference

Ramzy, G. M., Norkin, M., Koessler, T., Voirol, L., Tihy, M., Hany, D., McKee, T., Ris, F., Buchs, N., Docquier, M., Toso, C., Rubbia-Brandt, L., Bakalli, G., Guerrier, S., Huelsken, J., & Nowak-Sliwinska, P. (2023). Platform combining statistical modeling and patient-derived organoids to facilitate personalized treatment of colorectal carcinoma. Journal of Experimental & Clinical Cancer Research : CR, 42(1), 79. https://doi.org/10.1186/s13046-023-02650-z

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Published

2023-07-19

Issue

Section

Health & Physiology