How cellular transport can be explained with a flip book
Keywords:Transporter, Bacteria, Membrane
All cells, from bacteria to humans, need to be able to transport substances from their inside to the outside and vice-versa. To understand how this transport works, scientists often had to remove transporters from their natural environment to study them, which may significantly alter their behavior. What if a “cellular” flip book was created to better mimic a transporter’s motions?
Original article reference
Galazzo, L., Meier, G., Januliene, D., Parey, K., de Vecchis, D., Striednig, B., Hilbi, H., Schäfer, L. v., Kuprov, I., Moeller, A., Bordignon, E., & Seeger, M. A. (2022). The ABC transporter MsbA adopts the wide inward-open conformation in E. coli cells. Science Advances, 8(41). https://doi.org/10.1126/sciadv.abn6845
Copyright (c) 2023 Christina Elsner
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