UV light is not all bad for DNA

Quentin Laurent; Tyler Brown

doi:10.25250/thescbr.brk699

Authors

Quentin Laurent McGill University
Tyler Brown McGill University

DOI:

https://doi.org/10.25250/thescbr.brk699

Keywords:

DNA, Nanotechnology, Chemistry

Abstract

Could the cellular mechanisms that cause sunburns help creating more stable therapeutics? Studying the effect of ultraviolet light on strands of DNA put together in various structures, we have discovered that gentle irradiation could protect the DNA from being degraded. This overcomes a major hurdle for translation into clinics without requiring extensive modifications.

Author Biographies

Quentin Laurent, McGill University

Postdoctoral Research Fellow

Tyler Brown, McGill University

PhD student

Original article reference

Tyler M. Brown, Hassan H. Fakih, Daniel Saliba, Jathavan Asohan, Hanadi F. Sleiman, J. Am. Chem. Soc. 2023, in press, https://doi.org/10.1021/jacs.2c08808