The AF122 antibody recognizes the AChR subunit in murine muscle endplates by immunofluorescence
The recombinant antibody AF122 binds to the acetylcholine receptor (AChR) a subunit expressed in murine muscle endplates and can be detected by immunofluorescence in paraformaldehyde (PFA)-fixed tibialis anterior cryosections.
Graus YF, De Baets MH, Van Breda Vriesman PJ, Burton DR. Anti-acetylcholine receptor Fab fragments isolated from thymus-derived phage display libraries from myasthenia gravis patients reflect predominant specificities in serum and block the action of pathogenic serum antibodies. J Immunol. 1997; 158(4):1919-29. PMID: 9029134
Tzartos SJ, Changeux JP. High affinity binding of alpha-bungarotoxin to the purified alpha-subunit and to its 27,000-dalton proteolytic peptide from Torpedo marmorata acetylcholine receptor. Requirement for sodium dodecyl sulfate. EMBO J. 1983; 2(3):381–387. PMID: 11894953
- 2023-02-22 (2)
- 2020-01-14 (1)
How to Cite
Copyright (c) 2020 The author(s)
This work is licensed under a Creative Commons Attribution 4.0 International License.